Semaglutide is an injectable medicine used for adults with obesity (BMI >30) or overweight (excess weight/BMI ≥27) who also have weight-related medical problems. Semaglutide is a tool to help lose weight and keep the weight off.

• used with a reduced calorie meal plan and increased physical activity.
• should not be used with other Semaglutide-containing products or other GLP-1 receptor agonist medicines.
• It is not known if Semaglutide is safe and effective when taken with other prescription, over-the-counter, or herbal weight loss products.
• It is not known if Semaglutide can be used safely in people with a history of pancreatitis.
• It is not known if Semaglutide/Pyridoxine is safe and effective for use in children under 18 years of age

Semaglutide is available in various strengths. You will start at the lowest dose and increase the dose every 4 weeks until you reach the maintenance dose. We will monitor you closely every month. It is important to follow the dosing schedule weekly.

Syringes can be stored in the refrigerator from 36°F to 46°F (2°C to 8°C) or they can beat room temperature 46°F to 86°F for up to 28 days.

• Do not freeze
• You can take Semaglutide with or without food
• If you need to change the day of the week for your injection, you may do so as long as your last dose of Semaglutide was given 2 or more days before
• If you miss a dose of Semaglutide and the next scheduled dose is more than 2 days away (48 hours), take the missed dose as soon as possible
• If you miss a dose of Semaglutide and the next scheduled dose is less than 2 days away (48 hours), do not administer the dose. Take your next dose on the regularly scheduled day
• If you miss doses ofSemaglutide for more than 2 weeks, take the next dose on the regularly scheduled day or call the office to talk about how to restart your treatment

• Tell your physician if you are pregnant or plan to become pregnant. Semaglutide may harm your unborn baby. You should stop using Semaglutidetwo months before you plan to become pregnant.
• Do not use Semaglutide if you are breastfeeding or plan to breastfeed. It is not known if Semaglutide passes into your breast milk.

Nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, gas, stomach flu, heartburn

Semaglutide stays in the body for about 5 to 7 weeks after the last dose.

In a 68-week medical study of 1,961 adults living with obesity or excess weight with a related medical problem, adults lost -35 lbs (or ~15% body weight). People taking placebo in the study (not on medicine) lost an average of 6 lbs (or ~2.5% body weight). The average starting weight for both groups was ~232 lbs. Individual results may vary.

Your successful weight loss is heavily dependent on your compliance with your injections, diet, and exercise.

We recommend you follow the DASH diet. DASH stands for Dietary Approaches to Stop Hypertension.

The DASH diet is a healthy-eating plan designed to help prevent or treat high blood pressure. It also may help lower cholesterol linked to heart disease, called low density lipoprotein (LDL) cholesterol.High blood pressure and high LDL cholesterol levels are two major risk factors for heart disease and stroke.

Foods in the DASH diet are rich in the minerals potassium, calcium, and magnesium. The DASH diet focuses on vegetables, fruits, and whole grains. It includes fat-free or low-fat dairy products, fish, poultry, beans, and nuts.

The diet limits foods that are high in salt, also called sodium. It also limits added sugar and saturated fat, such as in fatty meats and full-fat dairy products.

The DASH diet is a balanced eating plan that helps create a heart-healthy eating style for life. There’s no need for special foods or drinks. Foods in the diet are at grocery stores and in most restaurants. The goal is to eat whole, fresh foods. Avoid canned foods as they are high in salt and preservatives.

When following DASH, it is important to choose foods that are:

• Rich in potassium, calcium, magnesium, fiber, and protein.
• Low in saturated fat.
• Low in salt.
• Vegetables: 4 to 5 servings a day. One serving is 1 cup raw leafy green vegetables, 1/2 cup cut-up raw or cooked vegetables, or 1/2 cup vegetable juice.
• Fruits: 4 to 5 servings a day. One serving is one medium fruit, 1/2 cup fresh, frozen, or canned fruit, or 1/2 cup fruit juice.
• Fat-free or low-fat dairy products: 2 to 3 servings a day. One serving is 1 cup milk or yogurt, or 1 1/2 ounces cheese.
• Lean meats, poultry, and fish: six 1-ounce servings or fewer a day. One serving is 1 ounce of cooked meat, poultry, or fish, or 1 egg.
• Grains: 6 to 8 servings a day. One serving may be 1/2 cup of cooked cereal, rice, or pasta, 1 slice of bread, or 1-ounce dry cereal. Avoid white foods (bread, rice, pasta). Eat whole-grain items.

Please tell us about all the medicines you are taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Semaglutide may affect the way some medicines work, and some medicines may affect the way Semaglutide works. Tell us if you are taking other medicines to treat diabetes, including sulfonylureas or insulin. Semaglutide slows stomach emptying and can affect medicines that need to pass through the stomach quickly.

You should not use if:

• you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• you have had a serious allergic reaction to Semaglutide or any of the ingredients in Semaglutide.
• You are pregnant or planning to become pregnant.

Before using Semaglutide, tell your healthcare provider if you have any other medical conditions, including if you:

• have or have had problems with your pancreas or kidneys.
• have type 2 diabetes and a history of diabetic retinopathy.
• have or have had depression, suicidal thoughts, or mental health issues.